Details of the Drug

General Information of Drug (ID: )

• #Ro5 Violations (Lipinski): 1:
  Molecular Weight (mw)
  Logarithm of the Partition Coefficient (xlogp)
  Rotatable Bond Count (rotbonds)
  Hydrogen Bond Donor Count (hbonddonor)
  Hydrogen Bond Acceptor Count (hbondacc)
• ADMET Property:
  Half-life: The concentration or amount of drug in body reduced by one-half in 3 - 5 hours [1]
  Metabolism: The drug is metabolized via the cytochrome P450 enzyme 3A4 []
  Vd: The volume of distribution (Vd) of drug is 2505 L []

References

• [1] Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds